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Rabbit Anti-SH3D20/PE-Cy7 Conjugated antibody (bs-19753R-PE-Cy7)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19753R-PE-Cy7
英文名稱 Rabbit Anti-SH3D20/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的SH3結構域結合蛋白D20抗體
別    名 ARHGAP27; CAMGAP1; CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; PP905; RHG27_HUMAN; Rho GTPase-activating protein 27; Rho-type GTPase-activating protein 27; SH3 domain containing 20; SH3 domain containing protein 20; SH3D20; SH3P20.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SH3D20
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]

Function:
Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1.

Subcellular Location:
Cytoplasm. Membrane.

Tissue Specificity:
Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer.

Similarity:
Contains 1 PH domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.
Contains 3 WW domains.

Database links:

Entrez Gene: 201176 Human

Entrez Gene: 544817 Mouse

Entrez Gene: 303583 Rat

Omim: 610591 Human

SwissProt: Q6ZUM4 Human

SwissProt: A2AB59 Mouse

SwissProt: Q6TLK4 Rat

Unigene: 205326 Human

Unigene: 397197 Mouse

Unigene: 17895 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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