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Rabbit Anti-Rabies virus Glycoprotein/BF350 Conjugated antibody (bs-2088R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2088R-BF350
英文名稱 Rabbit Anti-Rabies virus Glycoprotein/BF350 Conjugated antibody
中文名稱 BF350標記的狂犬病病毒糖蛋白抗體
別    名 Rabies virus G; RV Glycoprotein; Rabies virus.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Rabies virus Glycoprotein
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 Function:
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Subunit:
Homotrimer. Interacts with matrix protein.

Subcellular Location:
Virion membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Post-translational modifications:
Glycosylated and palmitoylated by host. Glycosylation is crucial for glycoprotein export at the cell surface. {ECO:0000269|PubMed:1587845, ECO:0000269|PubMed:9451021}.

Similarity:
Belongs to the lyssavirus glycoprotein family.

Database links:
Entrez Gene: 1489856 Rabies virus


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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