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Rabbit Anti-SLC19A1/Gold Conjugated antibody (bs-19802R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19802R-Gold
英文名稱 Rabbit Anti-SLC19A1/Gold Conjugated antibody
中文名稱 膠體金標記的溶質(zhì)載體家族蛋白19成員A1抗體
別    名 CHMD; FLOT 1; FLOT1; Folate transporter 1; FOLT; IFC 1; IFC-1; IFC1; Intestinal folate carrier 1; Intestinal folate carrier; OTTHUMP00000115459; OTTHUMP00000115460; Placental folate transporter; Reduced folate carrier; Reduced folate carrier protein; REFC; RFC 1; RFC; RFC1; S19A1_HUMAN; SLC19A1; Solute carrier family 19 member 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)運蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC19A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1) is a Protein Coding gene. Diseases associated with SLC19A1 include placental choriocarcinoma and thiamine-responsive megaloblastic anemia syndrome. Among its related pathways are Cell Cycle, Mitotic and Metabolism. GO annotations related to this gene include oxidoreductase activity and folic acid transporter activity. An important paralog of this gene is SLC19A2.

Function:
Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.

Subcellular Location:
Membrane.

Tissue Specificity:
Placenta, liver, and to a much smaller extent, in lung.

Post-translational modifications:
Heavily glycosylated.

Similarity:
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

Database links:

Entrez Gene: 6573 Human

Entrez Gene: 29723 Rat

Omim: 600424 Human

SwissProt: P41440 Human

SwissProt: Q62866 Rat

Unigene: 84190 Human

Unigene: 9042 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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