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Rabbit Anti-SLC47A1/BF488 Conjugated antibody (bs-9284R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9284R-BF488
英文名稱 Rabbit Anti-SLC47A1/BF488 Conjugated antibody
中文名稱 BF488標記的溶質載體蛋白家族47成員A1抗體
別    名 1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein AIM1; S45A2_HUMAN; SHEP5; SLC45A2; Solute carrier family 45 member 2; Underwhite.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC47A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

Function:
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

Subcellular Location:
Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles.

Tissue Specificity:
Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes).

Similarity:
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

Database links:

Entrez Gene: 55244 Human

Omim: 609832 Human

SwissProt: Q96FL8 Human

Unigene: 232054 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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