超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
voyeur精品偷窥,欧美大胆a视频,久久情侣视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HPV16 E4/APC Conjugated antibody (bs-20108R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20108R-APC
英文名稱 Rabbit Anti-HPV16 E4/APC Conjugated antibody
中文名稱 APC標記的人乳頭瘤病毒16型E4抗體
別    名 E4; Human Papilloma Virus; Human papillomavirus type 16 E4; Human papillomavirus type 16 E4; Protein E4; Human Papillomavirus 16 (E4); HPV16 E4; E4 protein (HPV16); VE4_HPV16; HPV16-E4; Probable protein E4.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HPV16 E4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The papillomavirus E4 open reading frame (ORF) is contained within the E2 ORF, with the primary E4 gene-product (E1∧E4) being translated from a spliced mRNA that includes the E1 initiation codon and adjacent sequences. E4 is located centrally within the E2 gene, in a region that encodes the E2 protein′s flexible hinge domain. Although a number of minor E4 transcripts have been reported, it is the product of the abundant E1∧E4 mRNA that has been most extensively analysed.

Function:
Plays several roles to favor viral DNA replication including disruption of host intranuclear speckles (termed ND10 body) organization, cell cycle arrest at the G2 phase and inhibition of cellular DNA replication, by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin. Additionally, E4 is found in inclusion bodies within the cytoplasm associated with host SRPK1, a splicing factor regulator. Therefore, E4 may regulate host splicing factors in order to favor expression of late viral transcripts. Late in the infectious cycle, E4 may also act to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.

Subunit:
Assembles into oligomeric complexes. Interacts with host SRPK1; this interaction may favor expression of late viral transcripts. Interacts with host cytokeratin components KRT8 and KRT18.

Subcellular Location:
Host cytoplasm. Host nucleus.

Post-translational modifications:
Phosphorylated by host ERK. The phosphorylation triggers a structural change that enhances keratin binding and protein stability.

Similarity:
Belongs to the papillomaviridae E4 protein family.

Database links:
Entrez Gene: 1489076 HPV16

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 粉嫩av一区二区三区入口 | 国产日产欧洲无码视频无遮挡 | 91大神一区二区三区在线观看 | 欧美精品一区二区三区久久久竹菊 | 99久久夜色精品国产网站 | 还珠格格第二部1至48集免费观看 | 久9久9色综合 | 人妻无码不卡在线视频 | 亚洲丁香久久 | 色噜噜狠狠成人网p站 | 久久精品国产av一区二区三区 | 国产精品一区二区免费不卡 | 飘雪影院手机免费观看免费动漫 | 日本添下边无码视频全过程 | 午夜久久久久久久久 | 91麻豆精品国产91久久久点播时间 | 欧美日韩欧美日韩在线观看视频 | 国产精品免费一区二区三区 | 99免费高清视频 | 99久久免费国产精品6 | 91av资源九色蝌蚪视频 | 99久久99久久免费精品小说 | 一区二区三区欧洲 | 四虎精品一区 | 国产成人福利在线观看 | 亚洲国产欧美在线观看片不卡 | 亚洲国产精品欧美久久 | 欧美最肥BBW毛 | 精品无人乱码一区二区 | 亚洲精品乱码久久久久久9色 | 婷婷色播婷婷 | 欧美人牲口杂交在线播放免费 | 中文字幕色婷婷在线视频 | 一级做a爰大片免费 | 国产99午夜精品一区二区三区 | 无遮挡十八禁污污网站免费 | 国产99午夜精品一区二区三区 | 国产69精品久久久久按摩 | 冲田杏梨AV天堂一区二区三区 | 欧美人与禽交片mp4 亚洲AV色福利天堂 久久久久久综合网天天 | 精品国产一区一区二区三亚瑟 |