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Rabbit Anti-MDH2/Biotin Conjugated antibody (bs-20126R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20126R-Bio
英文名稱 Rabbit Anti-MDH2/Biotin Conjugated antibody
中文名稱 生物素標記的線粒體蘋果酸脫氫酶2抗體
別    名 M MDH; Malate dehydrogenase 2, NAD (mitochondrial); Malate dehydrogenase; Malate dehydrogenase, mitochondrial; MDH; mdh2; MDHM_HUMAN; MGC:3559; mitochondrial; Mitochondrial malate dehydrogenase 2, NAD; Mor 1; MOR1; OTTMUSP00000026139.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MDH2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Subunit:
Homodimer.

Subcellular Location:
Mitochondrion matrix.

Post-translational modifications:
Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri-and tetraacetylations. Glucose also increases acetylation by about 60%.

Similarity:
Belongs to the LDH/MDH superfamily. MDH type 1 family.

Database links:

Entrez Gene: 4191 Human

Entrez Gene: 17448 Mouse

Entrez Gene: 81829 Rat

Omim: 154100 Human

SwissProt: P40926 Human

SwissProt: P08249 Mouse

SwissProt: P04636 Rat

Unigene: 520967 Human

Unigene: 297096 Mouse

Unigene: 1011 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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