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Rabbit Anti-DNCLI1/BF555 Conjugated antibody (bs-20152R-BF555)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20152R-BF555
英文名稱 Rabbit Anti-DNCLI1/BF555 Conjugated antibody
中文名稱 BF555標記的胞質動力蛋白輕鏈中間體1抗體
別    名 Cytoplasmic dynein 1 light intermediate chain 1; cytosolic; DC1L1_HUMAN; DLC-A; DNCLI1; dync1li1; Dynein cytoplasmic 1 light intermediate chain 1; Dynein cytoplasmic light intermediate polypeptide 1; Dynein light chain A; Dynein light intermediate chain 1; Dynein light intermediate chain 1 cytosolic; FLJ10219; LIC1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Chicken, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNCLI1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
DNCLI1 (Cytoplasmic dynein 1 light intermediate chain 1) is a 523 amino acid protein that consists of at least 3 heavy chains, 2 intermediate chains and 8 light chains. DNCLI1 may play a role in binding Dynein heavy chain to chromosomes or membranous organelles and also may regulate Dynein enzymatic activity by associating with heavy chains of the Dynein head.

Function:
Cytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. Cytomegalovirus strain AD169 is a laboratory-adapted strain and appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.

Database links:

Entrez Gene: 51143 Human

Entrez Gene: 235661 Mouse

Entrez Gene: 252902 Rat

SwissProt: Q9Y6G9 Human

SwissProt: Q8R1Q8 Mouse

SwissProt: Q9QXU8 Rat

Unigene: 529495 Human

Unigene: 128627 Mouse

Unigene: 228621 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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