超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
超碰97在线看,欧美xxxxhd高清,欧美激情A∨在线视频播放
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DLC1/RBITC Conjugated antibody (bs-20131R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20131R-RBITC
英文名稱 Rabbit Anti-DLC1/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的肝癌缺失基因1抗體
別    名 ARHGAP 7; ARHGAP7; Deleted in liver cancer 1; Deleted in liver cancer 1 protein; DLC 1; Dlc-1; DLC1; DLC1 Rho GTPase activating protein; FLJ21120; HP; HP protein; KIAA1723; p122 RhoGAP; RHG07_HUMAN; Rho GTPase activating protein 7; Rho GTPase-activating protein 7; Rho type GTPase activating protein 7; Rho-type GTPase-activating protein 7; StAR related lipid transfer (START) domain containing 12; StAR related lipid transfer protein 12; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain containing protein 12; START domain-containing protein 12.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  線粒體  表觀遺傳學  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, 
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 171kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DLC1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010].

Function:
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Subunit:
Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.

Subcellular Location:
Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Note=Colocalizes with EF1A1 at actin-rich regions in the cell periphery.

Tissue Specificity:
Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.

Post-translational modifications:
Phosphorylation at Ser-88 appears to control the dimer-monomer transition. According to PubMed:15193260, it is phosphorylated at Ser-88 by PAK1, however, according to PubMed:18650427, the DYNLL1 dimer is not accessible for PAK1 and the phosphorylation could not be demonstrated in vitro.

Similarity:
Contains 1 Rho-GAP domain.
Contains 1 SAM (sterile alpha motif) domain.
Contains 1 START domain.

Database links:

Entrez Gene: 10395 Human

Entrez Gene: 50768 Mouse

Entrez Gene: 58834 Rat

Omim: 604258 Human

SwissProt: Q96QB1 Human

SwissProt: Q9R0Z9 Mouse

SwissProt: Q63744 Rat

Unigene: 134296 Human

Unigene: 210875 Mouse

Unigene: 224563 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久草亚洲天堂 | www.亚洲国产 | 日本免费高清一区二区 | 久久久精品免费 | 男人a天堂2814 | аⅴ中文天堂最新版在线 | 日韩激情一区 | 国产精品粉嫩av | 91桃色视频在线观看 | 全免费A敌肛交毛片免费 | 色在线导航 | 91传媒麻豆激情在线观看 | 亚洲第一极品精品无码 | 好紧好滑好湿好爽免费视频 | 亚洲一区二区三区中文字幕在线观看 | 久操麻豆 | 2021在线精品自偷自拍无码 | 逼逼影视| 国产网站91 | 成人三级黄色片 | 国产精品福利在线看 | 黄色一视频 | 日本不卡一区视频 | 乱码午夜极品国产内射 | 91精品国产高清久久久久久 | 日韩国产欧美在线观看 | 99久久精品69堂 | 羞羞答答成人影院www | 超碰在线公开免费 | 日日日日日日日 | 51视频国产精品一区二区 | x8x8女性性爽爽在线观看 | 国产色视频网站2 | 天堂蜜桃一区二区三区 | 中文字幕无码精品亚洲资源网久久 | 中文字幕av伊人av无码av | 日本线在线 | 亚洲.www| 久久精品剧情 | 久碰香蕉线视频在线观看视频 | 国产成本人片无码免费 |