超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
超碰资源在线,亚洲国产wwwccc36天堂,四虎国产成人精品免费一女五男
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DLC1/AP Conjugated antibody (bs-20131R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20131R-AP
英文名稱 Rabbit Anti-DLC1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的肝癌缺失基因1抗體
別    名 ARHGAP 7; ARHGAP7; Deleted in liver cancer 1; Deleted in liver cancer 1 protein; DLC 1; Dlc-1; DLC1; DLC1 Rho GTPase activating protein; FLJ21120; HP; HP protein; KIAA1723; p122 RhoGAP; RHG07_HUMAN; Rho GTPase activating protein 7; Rho GTPase-activating protein 7; Rho type GTPase activating protein 7; Rho-type GTPase-activating protein 7; StAR related lipid transfer (START) domain containing 12; StAR related lipid transfer protein 12; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain containing protein 12; START domain-containing protein 12.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  線粒體  表觀遺傳學  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, 
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 171kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DLC1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010].

Function:
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Subunit:
Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.

Subcellular Location:
Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Note=Colocalizes with EF1A1 at actin-rich regions in the cell periphery.

Tissue Specificity:
Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.

Post-translational modifications:
Phosphorylation at Ser-88 appears to control the dimer-monomer transition. According to PubMed:15193260, it is phosphorylated at Ser-88 by PAK1, however, according to PubMed:18650427, the DYNLL1 dimer is not accessible for PAK1 and the phosphorylation could not be demonstrated in vitro.

Similarity:
Contains 1 Rho-GAP domain.
Contains 1 SAM (sterile alpha motif) domain.
Contains 1 START domain.

Database links:

Entrez Gene: 10395 Human

Entrez Gene: 50768 Mouse

Entrez Gene: 58834 Rat

Omim: 604258 Human

SwissProt: Q96QB1 Human

SwissProt: Q9R0Z9 Mouse

SwissProt: Q63744 Rat

Unigene: 134296 Human

Unigene: 210875 Mouse

Unigene: 224563 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产亚洲综合专区在线在线观看 | 国产女人高潮叫床免费视频 | 亚洲一区二区三区视频 | 在线观看一区二区三区国产免费 | 精品在线不卡 | 国产精品99久久久久久宅男 | 无码毛片一区二区本码视频 | 97激情| 国产ww久久久久久久久久 | 色94色欧美sute亚洲线路二 | 亚洲AV无码成人网站在线观看 | 日本污视频在线观看 | www.avtvtv.com新网址 | 日本一道本线一区免费 | 2020国产精品香蕉在线观看 | 久草视频手机在线观看 | 黑人大荫道BBWBBB高潮潮喷 | 91成人品| 成品片a免人看免费 | 欧美日韩在线资源 | 成人免费毛片立即播放 | 国产精品与欧美交牲久久久久 | 亚洲国产综合精品中文第一 | 午在线亚洲男人午在线 | 亚洲av色欲色欲www | 99精品国产自在现线10页 | 欧美日韩一区二区三区精品 | 国产色黄 | 999精品欧美一区二区三区黑人 | 午夜剧场91| 国产精品一区三区在线观看 | 青青草视频成人 | 亚洲色大成网站WWW在线观看 | 亚洲清纯国产 | 网站免费在线观看入口满十八 | 国产无遮挡又黄又爽网站 | 亚洲成人av一区二区三区 | 精品久久免费观看 | 成人一级黄色毛片 | 伊人久久久精品区aaa片 | 亚洲乱色 |