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Rabbit Anti-SLC30A4/APC Conjugated antibody (bs-21253R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-21253R-APC
英文名稱 Rabbit Anti-SLC30A4/APC Conjugated antibody
中文名稱 APC標記的溶質載體轉運蛋白家族30成員4抗體
別    名 Dri 27 protein; Lethal milk protein; Slc30a4; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 member 4; Zinc transporter 4; ZnT-4; Znt4; ZNT4_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Cow, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC30A4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]

Function:
Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.

Subcellular Location:
Endosome membrane.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
SLC30A subfamily.

Database links:

Entrez Gene: 7782 Human

Omim: 602095 Human

SwissProt: O14863 Human

Unigene: 162989 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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