超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
97国产视频,亚洲成网站在线播放观看,99精品久久久久久久
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DEF6/IBP/PE Conjugated antibody (bs-20306R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20306R-PE
英文名稱 Rabbit Anti-DEF6/IBP/PE Conjugated antibody
中文名稱 PE標記的干擾素調節因子4結合蛋白抗體
別    名 DEF-6; Def6; DEFI6_HUMAN; Differentially expressed in FDCP 6 homolog; Differentially expressed in FDCP 6 homologue mouse; IBP; IRF4-binding protein; Swap70 like adapter of T cells.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DEF6/IBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
DEF6 is a 631 amino acid protein that is widely expressed in T and B cells of the immune system. Localized to the nucleus, cytoplasm and cell membrane, DEF6 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) that functions to activate Rho GTPases such as Rac 1, Cdc42 and Rho A. Via its ability to activate various Rho GTPases, DEF6 can regulate cell shape, movement and polarity and, through its interaction with T helper cells, DEF6 can also help mediate the immune response. DEF6 contains one PH (pleckstrin homology) domain which is required for binding to phosphatidylinositol 3,4,5-trisphosphate and subsequent recruitment to the plasma membrane.

Function:
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP-70 signaling.

Subunit:
Interacts with ZAP70 (By similarity). Interacts with IRF4, activated RAC1 and F-actin. Both the phosphorylated and non-phosphorylated forms bind phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3).

Subcellular Location:
Cytoplasm. Cell membrane. Nucleus. Recruited to the plasma membrane upon binding phosphatidylinositol 3,4,5-trisphosphate.

Tissue Specificity:
Broadly expressed in the immune system and can be detected in T and B-cells.

Post-translational modifications:
Tyrosine-phosphorylated by tyrosine-protein kinase LCK in response to T-cell activation.

Similarity:
Contains 1 PH domain.

Database links:

Entrez Gene: 50619 Human

Entrez Gene: 23853 Mouse

Entrez Gene: 309642 Rat

Omim: 610094 Human

SwissProt: Q9H4E7 Human

SwissProt: Q8C2K1 Mouse

Unigene: 15476 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日本一区二区三区免费高清 | 国产精品国产自产拍高清 | 亚洲人成人一区二区三区 | 狠狠躁夜夜躁人人爽超碰97香蕉 | 亚洲AV无码AV制服丝袜在线 | 欧美黑人巨大精品VIDEOS | 大黄无码网站在线观看 | 国产三级精品久线在线观看 | 国产免费无遮挡吸乳视频 | 国产成人综合亚洲专区 | 亚洲AV永久中文无码精品综合 | 国产日韩精品一区二区三区在线 | 欧美美乳视频网站在线观看 | 久久久91麻豆精品国产一区 | 最近中文字幕在线中文视频 | 91操人 | 免费的av网站在线观看国产精品 | 91精品91久久久中77777老牛 | 成人欧美在线 | 水蜜桃在线观看视频 | 国产精品186在线观看在线播放 | 老司机久久一区二区三区 | 大伊人狠狠躁夜夜躁av一区 | 亚洲AV无码成人网站在线观看 | 狠狠躁夜夜躁人人爽超碰97香蕉 | 日日爽天天干 | 草碰在线 | 五月香丁激情欧美啪啪 | 婷婷激情影院 | 亚洲色成人一区二区三区小说 | 色八区人妻在线视频 | 老熟妇性老熟妇性色变态 | 中文字幕天天躁日日躁狠狠躁 | 成人看片在线观看 | 一级毛片影视 | 亚洲一区二区久久久 | 国产亚洲精品久久久久久老妇 | 久久久久亚洲波多野结衣 | 久久嫩草精品久久久精品才艺表演 | 性荡视频播放在线视频7777 | 欧美成年|