超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
免费看av网,999www视频免费观看,老司机99久久99精品免费播放
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DEF6/IBP/PE-Cy3 Conjugated antibody (bs-20306R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20306R-PE-Cy3
英文名稱 Rabbit Anti-DEF6/IBP/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的干擾素調節因子4結合蛋白抗體
別    名 DEF-6; Def6; DEFI6_HUMAN; Differentially expressed in FDCP 6 homolog; Differentially expressed in FDCP 6 homologue mouse; IBP; IRF4-binding protein; Swap70 like adapter of T cells.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DEF6/IBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
DEF6 is a 631 amino acid protein that is widely expressed in T and B cells of the immune system. Localized to the nucleus, cytoplasm and cell membrane, DEF6 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) that functions to activate Rho GTPases such as Rac 1, Cdc42 and Rho A. Via its ability to activate various Rho GTPases, DEF6 can regulate cell shape, movement and polarity and, through its interaction with T helper cells, DEF6 can also help mediate the immune response. DEF6 contains one PH (pleckstrin homology) domain which is required for binding to phosphatidylinositol 3,4,5-trisphosphate and subsequent recruitment to the plasma membrane.

Function:
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP-70 signaling.

Subunit:
Interacts with ZAP70 (By similarity). Interacts with IRF4, activated RAC1 and F-actin. Both the phosphorylated and non-phosphorylated forms bind phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3).

Subcellular Location:
Cytoplasm. Cell membrane. Nucleus. Recruited to the plasma membrane upon binding phosphatidylinositol 3,4,5-trisphosphate.

Tissue Specificity:
Broadly expressed in the immune system and can be detected in T and B-cells.

Post-translational modifications:
Tyrosine-phosphorylated by tyrosine-protein kinase LCK in response to T-cell activation.

Similarity:
Contains 1 PH domain.

Database links:

Entrez Gene: 50619 Human

Entrez Gene: 23853 Mouse

Entrez Gene: 309642 Rat

Omim: 610094 Human

SwissProt: Q9H4E7 Human

SwissProt: Q8C2K1 Mouse

Unigene: 15476 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 中文永久有效幕中文永久 | 插插射啊爱视频日a级 | 国产无套露脸视频在线观看 | 日韩精品免费视频一区二区三区 | 97人妻免费碰视频碰免 | 2021国产精品视频网站 | 91av网址 | 一区久久| 天天激情综合 | 人妻无码AV中文系列久久兔费 | 特级毛片A级毛片免费播放 婷婷久久久亚洲欧洲日产国码AV | 久久国产精品_国产精品 | 中文字国产精久久无 | 在线观看免费视频91 | 国产69精品久久久久99 | 麻豆视传媒 | 日韩精品无码一二区A片换脸 | 国产精品毛片av一区 | 欧美第2页 | 日日碰狠狠添天天爽 | 强●媚薬レズ狂いatid543 | 黄色手机在线观看 | 毛片毛片毛片毛片毛片毛片 | 亚洲永久网址在线观看 | 成年女人看片永久免费视频 | 色噜噜色狠狠 | 夜夜爽日日澡人人添小说 | 免费观看在线a级毛片 | 黄色在线观看免费 | 亚洲中国女厕嘘嘘40 | 中文字幕成熟丰满人妻 | 一夜新娘第三季在线观看 | 久久免费视频播放 | 最近中文字幕在线中文视频 | 丰满岳乱妇在线观看中字无码 | 91精品国产高清一区二区性色 | 人妻少妇被粗大爽.9797pw | 91首页| 久久免费公开视频 | 国产一区二区网站 | 免费观看男女性高视频 |