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Rabbit Anti-RASSF10/BF647 Conjugated antibody (bs-21165R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-21165R-BF647
英文名稱 Rabbit Anti-RASSF10/BF647 Conjugated antibody
中文名稱 BF647標記的RASSF10蛋白抗體
別    名 4632411J06Rik; Ras association (RalGDS/AF 6) domain family (N terminal) member 10; Ras association (RalGDS/AF-6) domain family (N-terminal) member 10; ras association domain containing protein 10; Ras association domain-containing protein 10; RASFA_HUMAN; RASSF10.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASSF10
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
RASSF10 (Ras Association Domain Family Member 10) is a Protein Coding gene. An important paralog of this gene is RASSF9.

Tissue Specificity:
Expressed in brain. Tends to be down-regulated in astrocytic gliomas due to promoter methylation. Methylation occurs early in gliomagenesis and the extent of methylation parallels with higher glioma grades, so that methylation is observed in close to 70% WHO grade IV primary glioblastomas, but not in grade I astrocytomas.

DISEASE:
During interphase, predominantly cytoplasmic, although some nuclear staining in several tumor cell contexts. During prophase, observed at developing centrosomes. Displays persistent localization with centrosomally radiating microtubule bundles until late telophase. Associates with spindle poles particularly during metaphase and anaphase before relocating back to the cytoplasm.

Similarity:
Contains 1 Ras-associating domain.

Database links:

Entrez Gene: 644943 Human

SwissProt: A6NK89 Human

Unigene: 134650 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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