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Rabbit Anti-PRPF4/BF555 Conjugated antibody (bs-20098R-BF555)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20098R-BF555
英文名稱 Rabbit Anti-PRPF4/BF555 Conjugated antibody
中文名稱 BF555標記的PRPF4蛋白抗體
別    名 HPRP4; HPRP4P; PRP4; PRP4 pre mRNA processing factor 4 homolog (yeast); PRP4/STK/WD splicing factor; Prp4p; U4/U6 small nuclear ribonucleoprotein Prp4; WD splicing factor Prp4; PRP4_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRPF4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]

Function:
Involved in pre-mRNA splicing.

Subunit:
Interacts directly with PRPF18, PPIH and PRPF3. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. This complex interacts with the U4/U5/U6 tri-snRNP complex.

Subcellular Location:
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.

Similarity:
Contains 7 WD repeats.

Database links:

Entrez Gene: 8899 Human

Entrez Gene: 19134 Mouse

Entrez Gene: 291078 Rat

Omim: 602338 Human

SwissProt: Q08DZ2 Cow

SwissProt: Q13523 Human

SwissProt: Q61136 Mouse

SwissProt: Q5RKH1 Rat

Unigene: 159014 Human

Unigene: 10027 Mouse

Unigene: 482253 Mouse

Unigene: 32654 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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