| 產品編號 | bs-23149R-BF488 |
| 英文名稱 | Rabbit Anti-PACAP receptor/BF488 Conjugated antibody |
| 中文名稱 | BF488標記的腺苷酸環化酶激活肽受體1抗體 |
| 別 名 | ADCYAP1 R1; ADCYAP1R 1; PACAP-R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1; PAC 1; PAC1; PAC1R; PACAP R 1; PACAP1 R; PACAPR; PACAPRI; Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; Pituitary adenylate cyclase activating polypeptide receptor; Pituitary adenylate cyclase activating polypeptide type I receptor precursor; PACR_HUMAN. |
| 規格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領域 | 細胞生物 免疫學 神經生物學 細胞膜受體 G蛋白偶聯受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PACAP receptor |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 |
background: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide belonging to the vasoactive intestinal polypeptide/glucagon/ secretin family. It is widely distributed in the body, and a variety of biological actions have been reported. Recent studies have shown that there is a family of PACAP receptors (PACAPRs), and two members of this family have been identified. This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract (By similarity). Belongs to the G-protein coupled receptor 2 family. Function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Subunit: Interacts (via N-terminal extracellular domain) with ADCYAP1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta. Similarity: Belongs to the G-protein coupled receptor 2 family. Database links: Entrez Gene: 117 Human Entrez Gene: 11517 Mouse Omim: 102981 Human SwissProt: P41586 Human SwissProt: P70205 Mouse Unigene: 377783 Human Unigene: 44245 Mouse Unigene: 88408 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 生長因子和激素（ Growth Factor and Hormones） PACAP 受體分為兩個亞型，PACAP-1型受體對PACAP是特異性的，與PACAP的親和力比VIP高100-1000倍，PACAP-II型受體與PACAP和VIP的親和力相似，對二者無選擇性。此抗體即為前者。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
