超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日本免费精品一区二区三区,青草久久免费视频,亚洲另类春色国产精品
首頁 > 產品中心 > 標記一抗 > 產品信息
Mouse Anti-Fibronectin/FN1/Biotin Conjugated antibody (bsm-33143M-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bsm-33143M-Bio
英文名稱 Mouse Anti-Fibronectin/FN1/Biotin Conjugated antibody
中文名稱 生物素標記的纖維連接蛋白單克隆抗體
別    名 CIG; Cold insoluble globulin; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; ED B; ED-B; fibronectin 1; FINC; FN 1; FN; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor; MSF; Transformation sensitive protein; FINC_HUMAN; Fibronectin; Cold-insoluble globulin; Ugl-Y3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  細胞粘附分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 1B9
交叉反應 Human,  (predicted: Mouse, Rat, )
產品應用 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 259kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fibronectin/FN1
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].

Function:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Subunit:
Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1. Interacts with FBLN7. Interacts with COMP. Interacts with S.aureus fnbA. Interacts with TNR; the interaction inhibits cell adhesion and neurite outgrowth. Interacts with FST3.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.

Post-translational modifications:
Sulfated.
It is not known whether both or only one of Thr-2064 and Thr-2065 are/is glycosylated.
Forms covalent cross-links mediated by a transglutaminase, such as F13A or TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers (e.g. fibrinogen-fibronectin, collagen-fibronectin heteropolymers).
Phosphorylation sites are present in the extracellular medium.
Proteolytic processing produces the C-terminal NC1 peptide, anastellin.

DISEASE:
Defects in FN1 are the cause of glomerulopathy with fibronectin deposits type 2 (GFND2) [MIM:601894]; also known as familial glomerular nephritis with fibronectin deposits or fibronectin glomerulopathy. GFND is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life.

Similarity:
Contains 12 fibronectin type-I domains. Contains 2 fibronectin type-II domains. Contains 16 fibronectin type-III domains.

Database links:

Entrez Gene: 280794 Cow

Entrez Gene: 2335 Human

Entrez Gene: 14268 Mouse

Entrez Gene: 25661 Rat

Omim: 135600 Human

SwissProt: P07589 Cow

SwissProt: P02751 Human

SwissProt: P11276 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

細胞粘附蛋白(Call Adhesion Protein)
FaN(Fibronectin)是一種細胞粘附蛋白,參與細胞粘附,分化,移動,傷口愈合,凝血和機體防衛。主要分布于結締組織及大部分基底膜上,作為判斷良惡性上皮源性腫瘤(如乳腺癌等)的一個主要參考指標,亦可作為惡性腫瘤轉移和病人預后的判斷指標
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 无遮挡又黄又刺激又爽的视频 | 国产十区 | 欧美成人一区二区三区 | 伊人天堂av无码av日韩av | 精品偷拍被偷拍在线观看 | 不卡视频一区二区三区 | 在线观看热码亚洲av每日更新 | 久久米奇亚洲 | 亚洲日韩中文第一精品 | 免费无码A片一区二区三区天美 | 午夜性福利 | 国产精品久久久久77777丨 | 成年在线网站免费观看无广告 | 欧美高清一区 | 91久久精品综合 | 亚洲无人区在线观看AV | 色婷婷av一区二区三区小说 | 99久久精品无免国产免费75 | 超碰97人人做人人爱少妇 | 亚洲v精品 | 久久人人妻人人爽人人卡片av | 免费一级黄色大片 | 91视频导航 | 特级淫片女子高清视频在线观看 | 亚洲一区二区二区久久成人婷婷 | 国产在线一区二区综合免费视频 | 天堂中文视频 | 欧美国产日韩久久MV | 亚洲欧美日本国产专区一区 | 久草在线视频免赞 | 亚洲黄色大片在线观看 | 最新在线视频 | 日本久久久久一级毛片 | 久热综合在线亚洲精品 | 久久超碰极品视觉盛宴 | 中国黄色三级毛片 | 国产成a人片在线观看视频99 | 欧美性色网站 | 国产精选视频 | 国产精欧美一区二区三区久久久 | 国产成人小视频 |