超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲精品无码AV中文字幕,久久九精品,国产精品天堂AVAV在线
Mouse Anti-Fibronectin/FN1/BF647 Conjugated antibody (bsm-33143M-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bsm-33143M-BF647
英文名稱 Mouse Anti-Fibronectin/FN1/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的纖維連接蛋白單克隆抗體
別    名 CIG; Cold insoluble globulin; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; ED B; ED-B; fibronectin 1; FINC; FN 1; FN; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor; MSF; Transformation sensitive protein; FINC_HUMAN; Fibronectin; Cold-insoluble globulin; Ugl-Y3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 1B9
交叉反應(yīng) Human,  (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 259kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fibronectin/FN1
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].

Function:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Subunit:
Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1. Interacts with FBLN7. Interacts with COMP. Interacts with S.aureus fnbA. Interacts with TNR; the interaction inhibits cell adhesion and neurite outgrowth. Interacts with FST3.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.

Post-translational modifications:
Sulfated.
It is not known whether both or only one of Thr-2064 and Thr-2065 are/is glycosylated.
Forms covalent cross-links mediated by a transglutaminase, such as F13A or TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers (e.g. fibrinogen-fibronectin, collagen-fibronectin heteropolymers).
Phosphorylation sites are present in the extracellular medium.
Proteolytic processing produces the C-terminal NC1 peptide, anastellin.

DISEASE:
Defects in FN1 are the cause of glomerulopathy with fibronectin deposits type 2 (GFND2) [MIM:601894]; also known as familial glomerular nephritis with fibronectin deposits or fibronectin glomerulopathy. GFND is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life.

Similarity:
Contains 12 fibronectin type-I domains. Contains 2 fibronectin type-II domains. Contains 16 fibronectin type-III domains.

Database links:

Entrez Gene: 280794 Cow

Entrez Gene: 2335 Human

Entrez Gene: 14268 Mouse

Entrez Gene: 25661 Rat

Omim: 135600 Human

SwissProt: P07589 Cow

SwissProt: P02751 Human

SwissProt: P11276 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

細(xì)胞粘附蛋白(Call Adhesion Protein)
FaN(Fibronectin)是一種細(xì)胞粘附蛋白,參與細(xì)胞粘附,分化,移動,傷口愈合,凝血和機體防衛(wèi)。主要分布于結(jié)締組織及大部分基底膜上,作為判斷良惡性上皮源性腫瘤(如乳腺癌等)的一個主要參考指標(biāo),亦可作為惡性腫瘤轉(zhuǎn)移和病人預(yù)后的判斷指標(biāo)
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 久久精品666 | 日韩欧美~中文字幕 | 欧洲色婷婷 | 日韩av一二三区 | 成全动漫在线观看免费观看 | 欧美丝袜一区二区三区 | 国产精品免费播放 | 无码人妻精品专区在线视频 | 97成人超碰视| 欧美伦理大片 | 韩日a级片 | 一本到无码av专区无码不卡 | 国产成人精品福利视频 | 国产一区中文 | 尤物av无码色av无码 | 手机看片日本 | 澳门四虎 | 亚洲日韩看片无码AV | 丰满的人妻HD高清日本 | 逼逼综合网 | 亚洲中文字幕久久无码精品 | 久久免费视频9 | av基地网| 欧美在线观看免费观看视频 | 一本大道香蕉在线视频 | 国产精品美女久久久久av毛片 | freesex18处xx柔术 | 另类天堂网不卡另类系列 | 老人把我添到了高潮A片 | 亚洲AV无码成H人动漫无遮挡 | 亚洲激精日韩激精欧美精品 | 国产特黄在线 | 久久精品人妻无码一区二区三区盗 | 亚洲国产成人久久一区www妖精 | 92精品视频| 日韩无砖专区一中文字目 | 欧美婷婷六月丁香综合色 | 亚洲二区中文字幕 | 久久国产中文娱乐网 | 亚洲乱码国产乱码精品精的特点 | 午夜精选视频 |