超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
97精品视频在线,国产麻豆精品精东影业AV网站,黄色一级片在线免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Mouse Anti-Fibronectin/FN1/BF594 Conjugated antibody (bsm-33143M-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bsm-33143M-BF594
英文名稱 Mouse Anti-Fibronectin/FN1/BF594 Conjugated antibody
中文名稱 BF594標記的纖維連接蛋白單克隆抗體
別    名 CIG; Cold insoluble globulin; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; ED B; ED-B; fibronectin 1; FINC; FN 1; FN; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor; MSF; Transformation sensitive protein; FINC_HUMAN; Fibronectin; Cold-insoluble globulin; Ugl-Y3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  細胞粘附分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 1B9
交叉反應 Human,  (predicted: Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 259kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fibronectin/FN1
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].

Function:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Subunit:
Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1. Interacts with FBLN7. Interacts with COMP. Interacts with S.aureus fnbA. Interacts with TNR; the interaction inhibits cell adhesion and neurite outgrowth. Interacts with FST3.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.

Post-translational modifications:
Sulfated.
It is not known whether both or only one of Thr-2064 and Thr-2065 are/is glycosylated.
Forms covalent cross-links mediated by a transglutaminase, such as F13A or TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers (e.g. fibrinogen-fibronectin, collagen-fibronectin heteropolymers).
Phosphorylation sites are present in the extracellular medium.
Proteolytic processing produces the C-terminal NC1 peptide, anastellin.

DISEASE:
Defects in FN1 are the cause of glomerulopathy with fibronectin deposits type 2 (GFND2) [MIM:601894]; also known as familial glomerular nephritis with fibronectin deposits or fibronectin glomerulopathy. GFND is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life.

Similarity:
Contains 12 fibronectin type-I domains. Contains 2 fibronectin type-II domains. Contains 16 fibronectin type-III domains.

Database links:

Entrez Gene: 280794 Cow

Entrez Gene: 2335 Human

Entrez Gene: 14268 Mouse

Entrez Gene: 25661 Rat

Omim: 135600 Human

SwissProt: P07589 Cow

SwissProt: P02751 Human

SwissProt: P11276 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

細胞粘附蛋白(Call Adhesion Protein)
FaN(Fibronectin)是一種細胞粘附蛋白,參與細胞粘附,分化,移動,傷口愈合,凝血和機體防衛。主要分布于結締組織及大部分基底膜上,作為判斷良惡性上皮源性腫瘤(如乳腺癌等)的一個主要參考指標,亦可作為惡性腫瘤轉移和病人預后的判斷指標
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 麻豆影视免费观看 | 9色porny自拍视频一区二区 | 五月网址 | 国产精品二区三区 | 97精品国产97久久久久久粉红 | 狠狠色婷婷久久一区二区三区 | 日产精品一卡2卡三卡四乱码 | 中文字幕第二页精品一区 | 日本特黄特色大片免费视频老年人 | 怦然心动2在线观看免费高清 | 免费观看的a级毛片的网站 国产精品高清视亚洲精品 波多野结衣乳巨码无在线播放 | 噜噜噜视频在线观看 | 黑人玩弄人妻中文在线 | 日本高清123 | 天堂va欧美ⅴa亚洲va | 偷偷草网站 | 国产精品一级毛片在线 | 欧美日韩一卡2卡三卡4卡乱码欧美孕交 | 天堂网WWW在线资源中文 | 在线观看亚洲AV日韩A∨ | 97SE亚洲国产综合自在线观看 | 一区二区三区不人妻无码 | 99久久精品国产交换 | 欧美又大又硬又粗BBBBB | 性荡视频播放在线视频7777 | 69免费观看 | 在线观看AV片永久免费 | www亚洲精品 | 337p日本欧洲亚洲大胆张筱雨 | 麻豆福利片 | 七天探花成人探花在线观看 | 给我看高清的视频在线观看片 | 成年女人18级毛片毛片免费 | 日本高清视频xxxxx | 国产好吊视频在线观看 | 亚洲欧美中文日韩v在线观看不卡 | 美女不带套日出白浆免费视频 | 在线亚洲欧美日韩精品专区 | 99热最新网址获取 | 一区二区精品在线观看 | 伊人七七 |