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Rabbit Anti-GCLM/Gold Conjugated antibody (bs-23361R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-23361R-Gold
英文名稱 Rabbit Anti-GCLM/Gold Conjugated antibody
中文名稱 膠體金標記的γ 谷氨酰半胱氨酸連接酶調節亞基抗體
別    名 Glutamate-Cysteine Ligase Modifier Subunit; Gamma-Glutamylcysteine Synthetase Regulatory Subunit; Glutamate--Cysteine Ligase Modifier Subunit; Gamma-ECS Regulatory Subunit; GCS Light Chain; GLCLR; Glutamate-Cysteine Ligase (Gamma-Glutamylcysteine Synthetase), Regulatory (30.8kD); Glutamate-Cysteine Ligase Modifier Subunit Delta2 Alternative Splicing; Glutamate--Cysteine Ligase Regulatory Subunit; Glutamate-Cysteine Ligase Regulatory Protein; Glutamate-Cysteine Ligase, Modifier Subunit; Gamma-Glutamylcysteine Synthetase; GSC Light Chain; GSH0_HUMAN;  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  免疫學  轉錄調節因子  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GCLM
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Function:
This protein is involved in step 1 of the subpathway that synthesizes glutathione from L-cysteine and L-glutamate.

Subunit:
Heterodimer of a catalytic heavy chain and a regulatory light chain.

Subcellular Location:
Cytosol

Tissue Specificity:
In all tissues examined. Highest levels in skeletal muscle.

Similarity:
Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.

Database links:

Entrez Gene: 2730 Human

Entrez Gene: 14630 Mouse

Entrez Gene: 29739 Rat

Omim: 601176 Human

SwissProt: P48507 Human

SwissProt: O09172 Mouse

SwissProt: P48508 Rat

Unigene: 315562 Human

Unigene: 292676 Mouse

Unigene: 2460 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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