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Rabbit Anti-Nkx2.6/HRP Conjugated antibody (bs-24101R-HRP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-24101R-HRP
英文名稱 Rabbit Anti-Nkx2.6/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的轉錄因子同源蛋白Nkx2.6抗體
別    名 CSX2; Homeobox protein NK-2 homolog F; homeobox protein NK2 homolog F; Homeobox protein Nkx-2.6; Homeobox protein Nkx2.6; NK2 homeobox 6; NK2 transcription factor related, locus 6 (Drosophila); NKX2-6; NKX26_MOUSE; NKX2F; NKX4 2; Tinman paralog.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞生物  發育生物學  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Mouse, )
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Nkx2.6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Constituents: 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin, 50% glycerol. Or Lyophilized. Buffer = 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin. Reconstitute with sterile distilled water.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011]

Function:
In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development.

Subcellular Location:
Nucleus

DISEASE:
A group of congenital heart defects involving the outflow tracts. Examples include truncus arteriosus communis, double-outlet right ventricle and transposition of great arteries. Truncus arteriosus communis is characterized by a single outflow tract instead of a separate aorta and pulmonary artery. In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. In double outlet of the right ventricle, both the pulmonary artery and aorta arise from the right ventricle.

Similarity:
Belongs to the NK-2 homeobox family. Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 137814 Human

Entrez Gene: 18092 Mouse

Omim: 611770 Human

SwissProt: A6NCS4 Human

SwissProt: P43688 Mouse

Unigene: 532654 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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