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Rabbit Anti-CD8/BF594 Conjugated antibody (bs-23448R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23448R-BF594
英文名稱 Rabbit Anti-CD8/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的CD8抗體
別    名 CD 8a; CD8 alpha chain; CD8; CD8 antigen alpha chain; CD8 antigen alpha polypeptide; CD8 antigen alpha polypeptide (p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; Leu 2; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; OTTHUMP00000160760; OTTHUMP00000160764; OTTHUMP00000203528; OTTHUMP00000203721; p32; T cell antigen Leu2; T cell co receptor; T cell coreceptor; T cell surface glycoprotein CD8 alpha chain; T lymphocyte differentiation antigen T8/Leu 2; T lymphocyte differentiation antigen T8/Leu2; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen; Cd8a; Lyt-2; Lyt2.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  干細(xì)胞  細(xì)胞表面分子  淋巴細(xì)胞  t-淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CD8
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

Function:
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

Subunit:
In general heterodimer of an alpha and a beta chain linked by two disulfide bonds. Can also form homodimers.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 925 Human

Entrez Gene: 926 Human

Entrez Gene: 12525 Mouse

Entrez Gene: 12526 Mouse

Omim: 186910 Human

SwissProt: P01732 Human

SwissProt: P10966 Human

SwissProt: P01731 Mouse

SwissProt: P10300 Mouse

Unigene: 405667 Human

Unigene: 85258 Human

Unigene: 1858 Mouse

Unigene: 333148 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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