超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
红色av社区,草草成人,福利片一区二区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-WEE1 /BF647 Conjugated antibody (bs-23526R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-23526R-BF647
英文名稱 Rabbit Anti-WEE1 /BF647 Conjugated antibody
中文名稱 BF647標記的WEE1蛋白抗體
別    名 DKFZp686I18166; EC 2.7.10.2; FLJ16446; Wee 1; WEE-1; WEE1 protein; Wee1 homolog; WEE1 homolog S. pombe; Wee1 like protein kinase; Wee1 tyrosine kinase; Wee1+ homolog; Wee1+ S. pombe homolog; WEE1A; Wee1A kinase; WEE1hu; WEE1 tyrosine kinase isoform 1; MGC105683; WEE1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  激酶和磷酸酶  通道蛋白  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 72kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human WEE1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Function:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated during M and G1 phases. Also autophosphorylated. Phosphorylation at Ser-642 by BRSK1 and BRSK2 in post-mitotic neurons, leads to down-regulate WEE1 activity in polarized neurons. Phosphorylated at Ser-53 and Ser-123 by PLK1 and CDK1, respectively, generating an signal for degradation that can be recognized by the SCF(BTRC) complex, leading to its ubiquitination and degradation at the onset of G2/M phase. Ubiquitinated and degraded at the onset of G2/M phase.

Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 7465 Human

Entrez Gene: 22390 Mouse

Entrez Gene: 308937 Rat

Omim: 193525 Human

SwissProt: P30291 Human

SwissProt: P47810 Mouse

SwissProt: Q63802 Rat

Unigene: 249441 Human

Unigene: 287173 Mouse

Unigene: 208255 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日韩一区二区在线观看 | 国产玉足榨精视频在线 | 日日夜视频 | 一级做a爰性色毛片免费1 | 久久婷婷五月综合色99啪 | 色网小说 | 大地资源在线观看免费中文版 | 欧美乱大交xxxxx春色视频 | 97天天干 | 影音先锋中文字幕亚洲资源站 | 丰满少妇被猛烈进入A片 | 青青草免费在线观看视频 | 日本高清免费一本视频100禁 | 一边摸一边桶一边脱免费视频 | 黄v在线观看 | 亚洲欧洲精品久久 | 性欧美1819sex性高播放 | 国模无码大尺度一区二区三区 | 超碰免费97 | 看曰本女人大战黑人视频 | 久久久av一区二区三区 | 在线观看国精产品一区 | 日韩免费不卡视频 | 日本亚洲国产一区二区三区 | 国产国产成年年人免费看片 | 国产伦码精品一区二区三区 | 黄色影视在线 | 一级欧美一级日韩片免费观看 | 日本国产亚洲系列 | 亚洲成A人一区二区三区 | 三年片免费观看大全在线观看了 | 综合激情久久综合激情 | 四虎影视久久久免费 | 久草国产在线 | 欧美a精品 | 国产精品久久久久久不久 | 一级a性色生活片久久毛片 国产精品香蕉 | 飞虎神鹰免费观看 | 无码免费午夜福利片在线 | 日日噜噜夜夜狠狠视频无码 | 国产精品欧洲 |